Category Archives: Science & Technology

A Taste of Penn State in our Nation’s Capital

Penn State’s Research on the Road speaker series closed out its first season yesterday evening with a stellar event at the National Press Club in D.C.  This was our second program (but hopefully not our last–ideas abound for spring semester!) with the enthusiastic folks from the DC area alumni chapter. The talk was titled “The Science of Wine Tasting: Can Anyone Learn to Taste the Nuances in Wine?” with food science assistant professor and sensory evaluation researcher John Hayes. 

 

About fifty us gathered in the Holeman Lounge at 6:30 p.m., many alumni coming straight from work, for half an hour of socializing and networking—and eating!—before the talk kicked off at 7.

Some alums were longtime chapter members, but some were new Penn State graduates just starting their careers in D.C.

Continue reading A Taste of Penn State in our Nation’s Capital

Tackling concussions

woman fitting EEG cap on volunteer
Research and services coordinator Katie Finelli fits a test subject with an EEG cap to help determine brain structure and function.

Concussions are scary and yet fairly common. My brother and I both experienced concussions before turning 18 — and given the numbers I’ve found, we are not an unusual family (at least not when it comes to head injuries). The CDC estimates that nearly 4 million concussions occur in the United States every year. And the NIH says that of those 4 million, about 1.5 million concussions occur in children.

This past spring Penn State formally opened the Center for Sport Concussion Research and Service. They are equipped with a virtual-reality facility as well as brain-imaging technology, including an fMRI (functional magnetic resonance imaging) and an EEG (electroencephalograph).

The new center has two main goals: to advance research in sport-related concussions and to provide services to local collegiate and child athletes by performing baseline assessments, which can help diagnose a concussion.

While working on an article for the Nov. 24 edition of the Beaver Stadium Pictorial football program, I learned that many athletic leagues are now requiring a doctor to sign off before a player is allowed back on the field after he or she sustains any head injury. This is not to say that 10 years ago, when my brother and I were in high school, concussions weren’t taken as seriously — but the importance of giving a traumatic brain injury enough time to heal is better understood now.

This understanding is in part due to the research that Sam Slobounov and Wayne Sebastianelli have been enmeshed in for many years. Slobounov is the director of the Center, as well as a professor of kinesiology and of orthopedics and medical rehabilitation. Sebastianelli is the principal investigator of the Center, and also serves as the director of athletic medicine and team physician for the Nittany Lions.

In a study published last December, Slobounov and colleagues reported that testing athletes for concussions may induce mental fatigue, whether or not the subject has a head injury. The results of the study advocate for baseline testing, something that the Center is providing for local athletes.

“Testing for a long period of time can induce fatigue,” Slobounov told me. “But at the same time, fatigue is a symptom of concussion. How do you rule out fatigue if you get fatigued while taking the test?”

As well as learning how quickly an athlete may become mentally fatigued, baseline testing includes gathering images of the brain so that a physician can compare the images pre- and post-concussion. The physician can then make an assessment of the injury and create a concussion management plan. This helps to minimize the athlete’s chances of suffering permanent brain damage by returning to play to soon.

Check out the full feature this Saturday in the football program when the Nittany Lions take on the Wisconsin Badgers!

Tobacco: An unlikely lifesaver

tobacco plants in greenhouse
Tobacco plants in Medicago greenhouse. Credit: DARPA

I recently had the opportunity to visit Research Triangle Park in North Carolina, when I attended the National Association of Science Writers annual conference. There are many perks to attending the NASW conference — including meeting amazing science writers and learning about the great research going on at other universities around the country. But one of my favorite perks is the field trips!

This year as part of the field trip portion of the conference, I visited the newest facility built by Medicago Inc. with 20 or so other science writers. While I had a general idea of what I was getting into — checking out a flu vaccine plant — I was in for a treat at this super-efficient greenhouse and laboratory.

When we rolled up on our tour bus, we were quickly escorted into a conference room where I swear a version of the cast of The Big Bang Theory awaited us. Everyone was friendly and seemingly eager to tell us all about what they do. And no wonder. They’re pretty much going to save the world.

Medicago — rhymes with Chicago — was basically given a challenge by DARPA (the Defense Advanced Research Projects Agency): create and perfect a process to produce 10 million doses of a pandemic influenza vaccine. Oh wait, and not just that — the process needs to take no more than a month.

My new Medicago friends rose to the challenge.

The most common way to develop a flu vaccine is to incubate the virus in a fertilized chicken egg. Medicago is using tobacco plants. The plants can be created more quickly and the virus incubation time in the tobacco plant is less than in the egg.

Medicago succeeded, and received a $21 million dollar grant from DARPA. So should the nation face a flu pandemic anytime soon, DARPA will call on them to produce these vaccines, stat.

We got a tour of their very new facilities — they were completed about a year ago — and saw the greenhouse and the equipment used to infiltrate the tobacco plants with the virus.

I might have been exaggerating a bit when I said Medicago is going to save the world, but their technology is pretty neat. And I think it’s awesome that we can do something healthy and possibly even life-saving with tobacco.

What will researchers come up with next?

“Moses Chan shows how science should be done.”

On a good day in the science writing business it’s not so much the breakthroughs that impress us. It’s the process, and the people.

Back in 2004, when Penn State’s Moses Chan and his graduate student Eun-Seong Kim reported the “probable observation of a supersolid helium phase” in a letter to Nature, they made headlines around the world. It was, as Science News noted this week, “one of the most exciting physics discoveries in recent years.”

What Chan and Kim had apparently discovered, after all, was nothing less than a brand new state of matter, “a mysterious substance that could float through ordinary solids like a ghost through walls,” according to physicsworld.com. Science News’ Alexandra Witze calls it “the stuff Nobel prizes are made of.”

In the eight years since, Chan, one of the University’s most distinguished (and most personable) researchers, has been attempting to repeat that amazing result. So have his colleagues in other condensed-matter labs around the world: trying either to uphold Chan’s finding or to knock it flat: this, after all, is the sober majesty of science.

Over the years, Witzke reports, there have been some experiments that seemed to confirm Chan’s observation, and others that did not, but none that has been found to be conclusive. John Beamish, a physicist at the University of Alberta in Canada, whose own work cast doubts on Chan’s result, notes, “It was continually surprising to those of us working in the field just how hard it was to confirm or disprove the existence of supersolidity.”

Chan himself went back to the drawing board relentlessly, rebuilding his experimental apparatus again and again, trying to eliminate any possibility of distorting effects. Repeating the initial experiment.

Last week, in a paper published in Physical Review Letters, he announced his new findings. They do not confirm his earlier conclusion, but reverse it. It was not the behavior of a supersolid that he and Kim observed in 2004, Chan now contends, but the ordinary stiffening of helium at extremely low temperatures.

I find Chan’s accompanying comments, reported in physicsworld.com, to be quietly compelling. He expresses, understandably, a sense of disappointment. It was “embarrassing, in a way,” he says, that the reinterpretation had taken so long. “It would have been nice,” he adds simply, [if supersolidity had held up], “but Mother Nature had her own way.”

Maybe all this is just par for the course. Maybe it is (or ought to be) less than remarkable. Moses Chan surely doesn’t need me to commend him, at any rate. But if we science writers are—and well we should be—ever quick to sound the claxons when a researcher cheats or cuts corners, I think it’s also worth noting when one of them so clearly models diligence and integrity.

Chan’s colleagues apparently agree. In the physicsworld.com article, Beamish praises him for pursuing the science “with amazing energy, even when his new experiments disagreed with his interpretation of his initial experiments.” An accompanying photo of Chan, lecturing recently in University Park, includes a fitting caption. It reads:

“Moses Chan shows how science should be done.”

Under the Sea: Mermaid Excluded

The city of Akko is on a peninsula surrounded by water.  Situated at the northern most point of greater Haifa Harbor, the Mediterranean surrounds the Old and New cities.

Maritime endeavors have always been important to the inhabitants of Akko, which was a Phoenician city during the Iron Age, and we all learned in grade school, or should have, that the Phoenicians were the sailors and traders of the Mediterranean Sea.

Interestingly, I’m surrounded by archaeologists who are totally interested in the Iron Age and they all agree, very little is actually known about the Phoenicians.  Looking at the Phoenicians is one of the objectives of the Total Archaeology @ Tel Akko project and while digging on the tel can tell us how they lived on land, exploring under the harbor might provide a clue as to how they lived on water.

Akko harbor is certainly known from Crusader history and during the Hellenistic period, the city was renamed Ptolomais and the harbor was very important.  Alexander the Great entered through Ptolomais on his way further east.

Hence the mermaid reference.  Supposedly, there is a female mermaid-like entity that appears near the Tower of Flies and asks, “Has he returned yet.”  She is supposedly asking after Alexander.

And the Tower of Flies, that too has a story.  When the Crusaders came to Akko or St. Jean d’ Acre, they thought they had reached Ekron, where one of the major deities was Ba’al Zevuv – Lord of the Flies (I kid you not).  Since the tower already existed and apparently garbage was dumped there frequently, the Crusaders named it the Tower of Flies.

But to the harbor. Centuries of sediment deposition from the small river that flows into the Mediterranean near Akko and natural ocean processes have undoubtedly changed the shoreline, covered evidence and filled in any number of harbor manifestations.  The only way to find the Phoenician harbor is to dig — underwater.

Total Archaeology@Tel Akko includes an underwater archaeology component and while they haven’t yet found the Phoenician harbor, they are bringing up some interesting results.